Abstract: In view of the current lack of systematicity and small number of computer information case bases, this article describes the relevant ideas and principles of case base construction based on the knowledge web weaving idea. Taking the direction of network information security as an example, the development process of planning, design, production and maintenance of the case database is proposed, and the creation and practice of the resource environment of the case database are carefully completed. This article provides an idea for reforming the teaching model and cultivating the innovative spirit and practical ability of professional degree graduates.