Abstract: This paper analyzes the problems in current course teaching and the characteristics of students, discusses the reform and practice of the teaching method of computer basic course guided by ability output. First of all, the modularity of teaching tasks is used to subdivide the unit knowledge, and ability output index is quantified throughout the teaching process such as project setting, teaching practice and evaluation method, thus improving the overall teaching effect. In addition, this paper adopts the flipped classroom teaching model in combination with students’ cognition rules, which both complies with the rule of education and embodies the urgent need of university computer basic course teaching reform.