Preparation and NMR Characterization of β-cyclodextrin Ibuprofen Supramolecular Inclusion Complex

Supramolecular chemistry is a new interdisciplinary research field at the intersection of modern chemistry, material science and life science. β-cyclodextrin( β-CD) is a kind of typical supramolecular structure, and its host guest interaction mechanism is widely used in the development of drug sustained-release agents. The introduction of this experiment is to observe the inclusion interaction of β-cyclodextrin and Ibuprofen by nuclear magnetic resonance ROESY and DOSY techniques, so as to help students understand the theory of small organic molecules and the structural characteristics of supramolecules, and proficiently use nuclear magnetic resonance spectrometer and spectral analysis.