Abstract: The indigenous development and fabrication of significant scientific instruments play a crucial role in rectifying deficiencies in China’s research instrument manufacturing capabilities and enhancing technological innovation. Shandong University has seamlessly integrated the research and development of a large-scale geological mechanics model testing system with laboratory construction. Building upon the foundation of autonomously developed experimental equipment, this approach has introduced a dependable new avenue for the construction of vital transportation infrastructure for our country. Empirical evidence underscores that the integration of indigenous instrument development and laboratory establishment not only yields remarkable scientific research outcomes but also furnishes robust support for addressing societal challenges and advancing national strategies. This harmonious fusion of efforts contributes valuable insights to the advancement of modernization in Chinese university laboratories.