Abstract: In view of the current situation of laboratory equipment management, starting from practical problems such as incomplete equipment management cycle, inconvenient equipment inventory, and security of equipment data, a laboratory equipment cycle management platform based on data encryption was designed and implemented. The platform realizes the full-cycle management of equipment from entry to use adjustment, maintenance, and scrapping to ensure the integrity of equipment information. On the basis of traditional Web-side management, QR code technology is used to associate equipment information to achieve one item with one code. By developing mobile applets, users can use equipment inventory, audit management, information management and other functions to improve the convenience of equipment management. Encryption algorithms are used to achieve secure storage of data and platform user identity authentication to enhance platform security.