Abstract: Animal laboratories are indispensable for advancing life science research and for the application of laboratory animals.With the advent of the “5G” era, the development of “smart laboratories” has become a key focus for higher education institutions. Consequently, the application of smart laboratory construction to management practices is also essential for the barrier environment of animal facilities. Using the Animal Model Center at the West China School of Stomatology of Sichuan University as a case study, a framework for constructing an intelligent management platform for barrier environments of animal facilities is explored. It discusses the application of the Internet of Things and the Internet in management in this context and highlights the advantages of establishing smart laboratories, aiming to provide reference for future smart laboratory development.