Abstract: Laser processing technology has become an important vehicle in the reform of engineering practice education in universities, owing to its advantages of high precision, efficiency, and flexibility. Focusing on the comprehensive innovative application of laser processing, this paper explores the integration of laser processing with multiple training platforms and manufacturing processes based on the platform of Center for Practice Innovation, targeting different participants. The application covers three practical teaching modules: comprehensive innovation courses, student-led independent practice, and faculty experiential activities. To fully harness the potential of laser processing, the curriculum encourages both students and participating instructors to utilize laser technology for independent innovative design and practical application. This initiative aims to enhance students’ abilities in independent innovation and practical application, enrich teachers’ approaches to teaching innovation, and ultimately advance the development of engineering practice education.