Abstract: Cultivating interdisciplinary talents with a comprehensive understanding of clinical needs and engineering technologies, integrating medical and engineering knowledge, and solving practical medical problems play a crucial role in safeguarding the people’s lives and health. As an important medical device for treating cardiovascular diseases, the manufacturing process of cardiovascular stents involves the integrated application of knowledge and technologies from numerous disciplines, making it an ideal medium for cultivating medical- engineering interdisciplinary talents. In the experiment, taking the construction of the femtosecond laser manufacturing process of cardiovascular stents as the starting point, students are trained to develop a thinking mode from the underlying principles to practical applications. They can establish a basic understanding of multiple disciplines such as machinery, control, optics, and software, and achieve software programming and stent manufacturing. Through such a systematic engineering training process, students can not only attain a profound comprehension of professional knowledge, but also accrue an extensive array of practical experiences, laying a solid foundation for their future academic research and work.