Abstract: To address the integration challenges between experimental teaching and scientific research, and to enhance the ability to cultivate comprehensive talents in coal mine safety engineering, the experimental teaching objectives are reverse-engineered based on Outcome-Based Education (OBE) to determine three levels of practical skills, innovative thinking, and comprehensive literacy. These objectives are integrated throughout the design of the basic coal spontaneous combustion experiment. The experimental results indicate that the fixed carbon content, CO concentration, and the concentration of alkane and alkene gases increase as particle size decreases. Based on the principles of identifying signature gases, a coal spontaneous combustion indicator system is established, and a cognitive process for the experiment is proposed. The connection and support between the basic coal spontaneous combustion experiment phase and the expected outcomes are effective, demonstrating that OBE is suitable for experimental teaching in coal mine safety engineering and serves the purpose of cultivating comprehensive talents.