Abstract: By leveraging the high-quality teaching resources of the college-level large-scale instrument sharing platform, this study constructs an innovative experimental teaching system through digital enhancement to improve university teaching quality. Guided by the concept of “integration of science and education”, scientific research achievements are incorporated into experimental teaching, optimizing the teaching content. The teaching functions of large-scale instrument platform are developed, and a digital experimental teaching platform is established. Utilizing internet technology, a blended online and offline teaching mode is adopted to strengthen students' independent learning and optimize the spatiotemporal arrangement of experimental teaching. A multi-dimensional evaluation system is implemented to assess learning outcomes and stimulate students' enthusiasm for learning. These reforms effectively enhance students’ professional core skills, fosters innovative thinking and abilities, and lays a solid foundation for their future professional and scientific research endeavors.