Abstract: Organic chemistry experiment teaching reform includes the teaching content,teaching method and teaching idea and so on,among which the improvement of students’ learning initiative is the key to the teaching reform.Based on the features of the chemical college course,the present conditions of our school,and the advantages of basic chemistry experiment center,the organic chemistry experiment teaching aim,content,teaching methods and means have changed significantly.Through experiment’s serialization and miniaturization,carrying out designing and opening experiments,using multimedia teaching,experiment teaching embodies “taking the student as the main body,focusing on the cultivation of students’ ability to cooperate,to find out the problems and problem solving ability,language expression ability,innovation consciousness and practical ability”,and gets better teaching effect in practice.