Abstract: In response to the current problems in comprehensive design of electronic system teaching, this paper applies the idea of CDIO to the course reform, according to the CDIO syllabus and standard, analyses it from four aspects which are project cognition, project planning, project implementation and project evaluation, propose some reform methods.The application of CDIO-based teaching mode can not only effectively cultivate the autonomous learning ability, the hand-on skills, teamwork ability, expression capability and comprehensive ability, increase innovate consciousness and thought, but also playe a positive role on improving teachers’ individual ability and comprehensive teaching level.