Abstract: Laboratory teaching is one of the important part in the teaching of universities.With the enlargement of enrollment, the problem of environmental pollution of laboratory has become a key and difficult problems.In this paper, according to the feature of randomness, high risk, complexity and high hazard of university laboratory pollution, through improving the laboratory management system, opening up the green experiment and laboratory processing with their own, the laboratory can effectively reduce pollutant emissions, and make a contribution to environmental protection.