Abstract: Universities with application technology play an important role in optimizing the structure of talents training about higher education and fostering high-level application technical talents.Universities with application technology must combine students‘ characteristics, mobilize students‘ interest on studying, strengthen the construction of practice teaching, increase the proportion of practice teaching effectively, and improve the comprehensive experimental ability constantly.At the same time, universities with application technology should also strengthen ties with enterprise, absorb the opinions of industry and reform cultivation programs, foster high-level application technical talents with the recognition of enterprise.