Abstract: The flipped classroom is a new teaching model.It reverses the process of the knowledge transfer and knowledge internalization,which transforms the role of the teachers and the students.This model provides a good environment and platform for students independent studying,and really reflects “students centered” education concept.According to the characteristics of instrumental analysis experimental teaching,it analyzes the feasibility and necessity of the flipped classroom teaching through flipped classroom model,and the flipped classroom teaching model of instrumental analysis experimental is proposed and implemented.The students’ study interest in taking the courses and subjective initiative and integrated ability were enhanced,and a good teaching effect was obtained.