Abstract: Instruments and equipments are the material basis of the experimental teaching center of undergraduate course teaching in the university, which are the hardware facilities to develop students' scientific research ability and innovation ability. In order to improve the efficiency of the use of laboratory equipment and effective management, this paper combines the reasonable configuration, management, repair maintenance and optimization of the equipment, takes all effective measures, achieves the reasonable allocation of equipment, standardizes the management and use of the system, improves the maintenance and maintenance system, cultivates a high level of experimental technology management team to ensure the normal use of equipment and resources sharing. It provides the beneficial resource for the improvement of experimental teaching effect and the cultivation of the high-quality talents.