Abstract: The design experiment is an experimental scheme between the basic teaching experiment and the innovative scientific research practice teaching. Taking the synthesis of benzoin as an example,this paper explores several main aspects of organic chemistry design experiments such as topic selection, knowledge preparation,program and implementation,summary and evaluation. It was proved that the introduction of organic chemistry design experiments in organic chemistry experiment teaching can improve students' interest in chemistry experiment learning and subsequent scientific research work,and contribute to the cultivation of students' innovative ability and improvement of comprehensive quality.