Abstract: Teaching exploration of comprehensive design experiments based on photoelectric information detection system has been made in our university. Seven experimental items are built up for the light wave parameter modulation, signal demodulation system, optical sensing system, and optical fiber sensing system. The experiments cover intensity, phase, polarization, wavelength modulation method and signal demodulation of light wave, one dimensional and three dimensional photoelectric measurements, and single point, array, and distributed structures. Taking the system design of filament diameter measurement by laser diffraction as an example, we discuss on how to carry out a comprehensive design experiment and how to guide students to design and build a system of photoelectric information detection in this paper. Our target is to cultivate students’ engineering oriented application ability and innovation ability.