Abstract: Focusing on the construction and reform of pharmaceutical experiment courses, an effective management mechanism of experimental teaching that applies to the innovative pharmaceutical talent training was explored in West China School of Pharmacy of Sichuan University. A novel quality evaluation system for experimental teaching that conforms to course features, universal coverage, multi dimensions and easy operation is constructed. After several years of curriculum construction and teaching reform based on evaluation, a long-term mechanism of laboratory construction and laboratory teaching management is established gradually. As a result, it may promote the curriculum construction and deepen the experimental teaching reform, thereby providing useful information for training first-class undergraduate pharmaceutical talents for Chinese universities.