Abstract: Problems of traditional enterprise resource planning（ERP） experiment teaching remain in terms of poor sense of reality, rigid model, insufficient interaction and unclear hierarchy. Having combined the background of innovation and entrepreneurship education, this paper has introduced the scenario simulation teaching method into ERP experiment teaching process by means of “manual simulation + software emulation”. From four aspects of managing scenario creation, preparing props & material, role play & simulation, and assessment of experimental score, this paper has redesigned and optimized the experiment content by tightly bridging ERP scenario simulation teaching and innovation and entrepreneurship education, in a bid to explore a new model of ERP experiment teaching that boosts innovation and entrepreneurship education with professional education.