Abstract: The engineering education professional accreditation is a good opportunity to normalize and strengthen the professional connotation construction. Guided by the outcome based education (OBE) concept that focuses on the student-centered, output-oriented and continuous improvement, construction of standardization is carried out in the bioengineering specialty of Lanzhou Jiaotong University for the following areas, the training system of practical teaching course, engineering practical teaching ability of teachers, practical teaching methods, quality monitoring and continuous improving system of teaching procedures, among others. In addition, research features are combined to put forward measures of reform, build the practical teaching system that has subject characteristics and conforms to engineering education professional accreditation standards, thereby improving practical teaching quality.