Abstract: Aiming at solving the problems of students’ low participation and poor teaching effect in the traditional teaching of instrumental analysis experiment, the self-designed instrumental analysis experiment with students as the main body is proposed in this paper. Taking the inductively coupled plasma atomic emission spectroscopy as an example, the detailed implementation process of the self-designed experiment teaching is introduced. It emphasizes that the development of the self-designed experiment should be based on a sufficient basic knowledge database, complete autonomy and effective course assessment of students in the whole experiment process. The students’ self-designed instrumental analysis experiment can enhance students’ understanding and mastery of basic theoretical knowledge, exercise their basic experimental skills and instrument operation ability, and improve their practical ability in scientific research to cultivate scientific and technological talents of the times.