Abstract: The ability to resolve practical problems and design new devices for engineering based on the learned knowledge, is an important teaching aim for practical course. Taking college physics experiments as an example, the advantage of the integration of open experiment and online teaching is analyzed in view of advancement, innovation and challenge. Teaching method, teaching strategy, teaching content and examination way are considered in our investigation. It is found that prepare lessons before class and group-explore learning are important steps for online and offline mixed teaching. Finally, the reforming effect and satisfaction are analyzed based on the questionnaire. Our investigation provides valuable guidelines on improving mixed teaching of practical course.