Abstract: Following the principle of “combination of virtual and real, no necessary to be virtual again for the real, and supplement real with virtual”, and simulating highly the actual engineering conditions (material, water quality, temperature and pressure) of the food water, condensate water and closed cooling water in power plants, and simulating the conditions, instrument operation, scheme design and experimental data of offline autoclave hanging test, the design of the experimental scene, experimental mode and assessment method of the “virtual simulation experiment of corrosion and protection of carbon steel in the deionized water”, is mainly discussed in the paper.