Abstract: This paper analyzes the problems existing in the laboratory infrastructure, network link type and data communication equipment, practical teaching development, laboratory management and maintenance of the traditional experimental platform of network engineering major under the background of the development of new engineering, and adopts the simulator and virtual machine software provided by IT vendors and open source projects to solve these problems, and compares the Cisco Packet Tracer simulator, the open source project GNS3, the Oracle VM VirtualBox and EVE-NG software work characteristics, describes the reference cases and deployment suggestions of the core courses of network engineering majors on the virtual simulation experimental platform, and illustrates that it is completely feasible and effective to combine virtual and real experiments on the virtual simulation experimental platform of network engineering major based on the above simulators and virtual machine software.