Abstract: With the gradual deepening of the “double first-class” construction of modern universities, the wide and flexible application of large-scale instrument sharing platforms will become a major boost for scientific research. The use training of the instrument is an important foundation for the sustainable development of large-scale instrument sharing platforms. In the context of the rapid development of informatization teaching, relying on smart teaching tool “Rain Class” to create a new training model of “online classroom” equipment can make up for the deficiencies of the existing training model for large instruments. Taking the total organic carbon analyzer as an example, we explored how to create a new training model for the use of large-scale instruments, and explained in detail the changes that the new training model has brought to the training and learning process. It has been verified that the establishment of a new large-scale instrument training model can not only improve the operating efficiency of the instrument, but also exercise students’ comprehensive innovation ability and serve for the construction of “double first-class” high-level disciplines and cultivation of talents in universities.