Abstract: Laser processing technology has become a crucial component in the reform of engineering practice education in universities, owing to its advantages of high precision, efficiency, and flexibility. This study focuses on the comprehensive innovative application of laser processing, leveraging the Engineering Practice Innovation Center platform to explore the integration of laser processing with multiple training platforms and manufacturing techniques. The approach targets three key educational modules: comprehensive innovation courses, student-led independent practice, and faculty experiential activities. To fully harness the potential of laser processing, the curriculum encourages both students and participating instructors to utilize laser technology for independent innovative design and practical application. This initiative aims to enhance students' autonomous innovation capabilities, diversify teaching methodologies for educators, and ultimately advance the development of engineering practice education.