Abstract: The lattice structure, formed by the ordered arrangement of interconnected nodes and struts, is characterized by lightweight properties, load-bearing capabilities and energy absorption, and has been widely applied in engineering fields. However, the lattice structure that is composed of a single unit-cell type arranged periodically may struggle to balance comprehensive performance across multiple performance dimensions. This paper constructs hybrid lattice structures by combining unit cells with different structural configurations and explores the compression behavior and energy absorption properties of these hybrid configurations. The mechanical response of the structure is investigated through uniaxial compression experiments, and the mechanical properties and deformation modes of the single-configuration structure are compared with those of the hybrid configuration. A quantitative and comprehensive assessment of the energy absorption performance of the lattice structure is conducted using the complex proportional assessment method. The results show that, compared with the single-configuration structure, a reasonable combination of structural configurations can integrate the functional characteristics of each constituent configuration, thereby improving the compression performance of hybrid configurations and achieving more stable and balanced energy absorption performance. The proposed design strategy for the hybrid structural configuration provides theoretical guidance and design basis for the development of novel energy-absorbing structures based on lattice structures.