Abstract: Heating equipment has become a core inducing source of safety accidents such as fires, explosions, and personal scalds in university laboratories, and the targeted nature and scientific nature of its safety management have become an urgent need for laboratory safety development. Based on the characteristics of heating equipment usage scenarios and actual management situations in universities, this study constructs a WSR-TSS-EWM theoretical comprehensive evaluation model for heating equipment from three dimensions—the objective laws of objects, the management logic of affairs, and the subjective factors of humans—using scenario construction theory as a tool and integrating the objective quantification advantages of the entropy weight method (EWM). The results show that this model can scientifically analyze the internal coupling mechanism of heating equipment safety risks, accurately present the action paths and weight differences of various risk factors, and provide solid theoretical support and practical guidance that can be implemented for the precision prevention, hierarchical control, and emergency response of heating equipment safety accidents in university laboratories.