Abstract: Microscopic interactive teaching system makes modern information technology fuse into biological experiment teaching, by taking advantage of the system‘s features such as real-time display, process monitor, interactive and timely feedback. To reform the traditional teaching, the system could improve the communication between teachers and students, inspire the students‘ interest in learning, enhance students‘ practical skills. Using the system could largely enhance the efficiency and quantity of experimental teaching, improve the comprehension of the biological basic conception. On the other side, it also demands a higher requirement of teaching methods and lab management.