Abstract: Cloud computing is a new distributed computing model. Cloud computing technology can break unequalization of experimental resources, which can be unified management so that the software and hardware resources of virtual experiment of colleges and universities can be reasonable scheduled. Combined with the basic chemical experiment teaching of Huaide College, this paper preliminarily discussed some problems of the informatization construction, the resource integration and so on, built some models such as basic chemical experiment teaching environment, virtual experiment teaching platform, experimental management under the cloud computing environment and probed the main contents of experiment evaluation and communication system. The aim is to help high quality construction of experimental teaching of independent college.