Abstract: Based on the framework of medical imaging physics, the teaching reform on magnetic resonance imaging (MRI) experiments has been explored and practiced. The content of experiment has been reconstructed and optimized according to the aims of course. By means of experiment design, we reform the organizational process of experiment teaching and lead students to analyze problems seriously and solve them actively, make students become the subject of experiment teaching. The advantage of experiment teaching in aspects of linking theory with practice and training students with practical ability has been demonstrated, in order to lay the foundation to achieve goals of teaching and cultivate students with professional ability.