Abstract: With more and more demand of the sophisticated instruments for experiment teaching and scientific research in university,the using and management of opening sophisticated instruments become the problems to be solved urgently.For promoting management mode and improving teaching quality,Shenyang Pharmaceutical University which apply database and dynamic website technology develop biology experimental teaching center web booking system for opening sophisticated instruments,establish the system module,and improve the management program.The system solves effective utilization and scientific management of opening sophisticated instruments,and it will promote the future development of biological experimental teaching center greatly.