Abstract: Practice teaching is an important part in high Uniersity and Colleges. In order to investigate GIS professional school-enterprise cooperation practice teaching base construction, the overall goal of innovation and practice ability was set for geographical information science students in this paper. Construction ideas were built for around a core, mobilizing the enthusiasm of both, the implementation of triple-planning, clearing four contents, establishing five kinds of mechanism. Measures and construction methods were put forward in innovative practice base team, base open laboratory, innovative practice teaching system, integration of production-study-research, base management and operation, to develop the GIS professional practice and innovative talents.