Abstract: In order to enhance students’ system ability, the practical teaching of embedded system design course is reformed. We have designed a comprehensive experiment in embedded system design course using single chip microcomputer. The comprehensive experiment can provide practice environment and can help students to hold the principle and design method of embedded systems. All projects in the comprehensive experiment are based on actual needs. Students are asked to complete the process of embedded system development and implementation in group. The investment to build the comprehensive experiment system is less, but the effect is better. The comprehensive experiment of embedded system design has been done by four grades students of computer engineering. And our practical results are very well.