Abstract: Open laboratory construction is an important content of experimental teaching reform in colleges and universities. Liberal arts laboratory can be divided into three types: professional course laboratory,basic course of professional laboratory,and public basic laboratory of liberal arts. Construction of comprehensive experimental teaching system for liberal arts is an effective mode of open laboratory,including foreign culture experience module,economic management and tourism module,actual combat simulation module,art appreciation and handmade module,and innovation and entrepreneurship module. We can construct opening support system of liberal arts laboratory as follows: strengthening the construction of informatization,opening to the students community,intercollegiate sharing,and stability the experiment teaching team.