Abstract: The pharmacy experimental teaching is an important link in practice teaching for cultivating of high quality innovative pharmaceutical talents. It involves broad technical field and high interdisciplinary relevancy resulting in many unsafe factors in the laboratory that are extremely complex,and leading to high requirement and difficulty of safety management for laboratory. Meanwhile,laboratory in different disciplines of pharmacy has different characteristics,and exists different safety problems and countermeasures. In recent years,the pharmacy experimental center of West China School of Pharmacy has made valuable exploration and practice in safety management for laboratory by strengthening the safety management software and hardware,with emphasis on laboratorial infrastructure construction.