Abstract: According to the requirements of the training program of pharmaceutical professionals and the investigation of the students’ questionnaire, the reform of the organic chemistry experiment teaching system of pharmacy specialty was carried out. Firstly, starting from the reform of teaching content, the contents and orders of the experiments had been adjusted once more, it can strengthen the students’ abilities of practice and innovation. The students can develop the habits to find and solve the problems gradually by reforming the teaching methods. The examination index of organic chemistry experiments can be quantitative tested by reform of the evaluation system, and the achievement of experiments can be evaluated objectively. The practice of the reform can fully arouse the enthusiasm of the students’ learning, and it can improve the teaching quality of organic chemistry experiments.