Abstract: In order to improve the teaching quality and inspire the students learning interest,this paper investigated the current situation of Biochemistry Teaching in the Kashi university through questionnaires and interviews. Analyzed the main factors of the teaching effects of Biochemistry curriculum in minority areas.The exploration has been done from the teaching content, teaching mode and teaching method of the course. The suitable teaching method was formed gradually. The teaching quality of biochemistry is improved effectively through a series of reforms. The paper shows that the heuristic teaching can improve the teaching quality of the students from the passive acceptance of knowledge to the active exploration of knowledge.