Abstract: Electric Circuit Comprehensive Experiment plays an important role on improving the electronic system design and practical ability of students,the quality of the experiment and the experimental effect are closely related.Firstly,we designed a project on integrated application of operational amplifier case which includes the typical circuits of operational amplifier skillfully.Secondly,according to the requirement of project,designed circuit parameters through theoretical analysis and calculation,then used Multisim of EDA software to simulate.Finally,the problems encountered during the experiment were analyzed.It comprehensively introduced the experimental research methods from project selection to theoretical design and practical adjustment.Then the actual test was conducted to analyze the causes and solutions of the problems.From the proposal of the case to the theoretical design and practical commissioning,the method of experimental project research is fully demonstrated,which can provide reference for other universities to set up the comprehensive experiment of electronic circuits.