Abstract: The comprehensive biological engineering experiment is very important teaching link to train college students' professional skills,improve the quality of comprehensive engineering and enhance their practical abilities.Aiming at the problems existing in the current experimental teaching process of bioengineering specialty,this paper proposes a student oriented research teaching concept.The main contents of the research and implementation are introduced from the three aspects of the reform:reforming contents of experimental course;improving methods of experimental teaching;and establishing diversified criteria of assessment,and a new model of the experimental teaching of biological engineering is constructed.Finally,the implementation effect is evaluated,and good results have been achieved in promoting experimental teaching effect and improving students' innovative and practical ability.