Abstract: In view of the country’s current policy orientation in the cultivation of practice and innovative talent, aiming at the limitation of the analog electronic technology experimental course, the paper proposes the idea of using Multisim to solve the problem of the limitations in the traditional analog electronic technology experimental course. The use of Multisim for electronic circuit design has advantages of simple operation, convenient parameter adjustment and analysis, intuitive presentation of result, and can easily carry out complex experimental projects like comprehensive experiment and designing experiment which can’t be easily achieved in the traditional laboratory environment. It can greatly improve students’ ability to apply theory to practice and the innovative practical ability, and improve their learning initiative and interest. Feedback indicates that the method is effective in improving experimental teaching quality, it will be a trend to use Multisim for related courses.