Abstract: The electron microscope public laboratory of “Materials Testing and Analysis Center” is a university-level registered laboratory with public service based on the “double first-class” construction of materials science and engineering in Shanghai Jiao Tong University. After years of laboratory opening, an efficient, standardized and normalized management operation mode has been gradually formed from the testing and analysis service, supporting experimental teaching to experimental innovation and development. On the one hand, the laboratory can provide high-quality test and analysis services, ensure high-quality experimental data, strongly support the experimental research of university research teams, and help the technical cooperation of off-campus units. On the other hand, the laboratory undertakes the cultivation of high-quality talents and plays an important role in the experimental technology and equipment training, experimental teaching construction and reform, practical technical guidance and analysis support. In addition, combined with the key management and technical problems of public laboratory, innovative experimental management methods, standardized experimental process and equipment function development have improved the efficiency of laboratory opening up and the service ability of technicians.