Abstract: Based on the teaching philosophy of student-centered and training target-oriented, centering on the construction of the curriculum system of step-by-step improvement, the course of Basic Experiment of Material Science has implemented a comprehensive innovation, including the transformation of teaching ideas, the optimization of teaching content and the enrichment of teaching methods. The characteristic experimental module integrated with scientific research and innovation elements is developed, combined online resources with offline teaching, and coordinated the open experimental teaching mode, which promotes the achievement of the course objectives and the cultivation of innovative talents in the major of materials science and engineering.